A Host-guest System for Understanding Protein-nanoparticle Interactions
نویسندگان
چکیده
منابع مشابه
Mass Spectrometric Detection of Nanoparticle Host–Guest Interactions in Cells
Synthetic host-guest chemistry is a versatile tool for biomedical applications. Characterization and detection of host-guest complexes in biological systems, however, is challenging due to the complexity of the biological milieu. Here, we describe and apply a mass spectrometric method to monitor the association and dissociation of nanoparticle (NP)-based host-guest interactions that integrates ...
متن کاملModulation of protein dimerization by a supramolecular host-guest system.
Two sets of cyan and yellow fluorescent proteins, monomeric analogues, and analogues with a weak affinity for dimerization were functionalized with supramolecular host-guest molecules by expressed protein ligation. The host-guest elements induce selective assembly of the monomeric variants into a supramolecular heterodimer. For the second set of analogues, the supramolecular host-guest system a...
متن کاملRabies Infection: An Overview of Lyssavirus-Host Protein Interactions
Viruses are obligatory intracellular parasites that use cell proteins to take the control of the cell functions in order to accomplish their life cycle. Studying the viral-host interactions would increase our knowledge of the viral biology and mechanisms of pathogenesis. Studies on pathogenesis mechanisms of lyssaviruses, which are the causative agents of rabies, have revealed some important ho...
متن کاملElectrostatic Interactions in Host-Guest Complexes
In this article the quantum chemically calculated charge density distribution of 18-crown-6 and the K+ . . .l8-crown-6 complex are compared with the charge density distribution of smaller molecules and corresponding complexes which can be considered as fragments of the 18-crown-6 molecule. An analysis of the charge density distribution in terms of atomic charge distribution according to the sto...
متن کاملHost-guest interactions in acid-porphyrin complexes.
In this report we use the weak interactions of acid-porphyrin complexes to selectively bind competing acids to the faces of a rigid cyclic porphyrin dimer, and characterise the resulting interactions by NMR spectroscopy and nano-electrospray ionisation spectrometry.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2020
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2019.11.2061